BDBM50153438 CHEMBL3774873::US9630914, Example 14

SMILES CCCCCCCCNC(=O)Oc1cccc(c1)-c1ccc(cc1F)C(C)C(O)=O

InChI Key InChIKey=RGAHGOAZFYSXHM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153438   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153438(CHEMBL3774873 | US9630914, Example 14)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153438(CHEMBL3774873 | US9630914, Example 14)
Affinity DataIC50:  2.90E+4nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In DepthDetails US Patent